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CAS RN: 73590-58-6 | 產品號碼: O0359
| 產品號碼 | O0359 |
純度/分析方法 
|
>98.0%(T)(HPLC) |
| 分子式 / 分子量 | C__1__7H__1__9N__3O__3S = 345.42 |
| 外觀與形狀（20°C） | Solid |
| 儲存條件
|
Refrigerated (0-10°C) |
| 儲存在惰性氣體下 | Store under inert gas |
| 應避免的情況 | Light Sensitive,Air Sensitive,Heat Sensitive |
| CAS RN | 73590-58-6 |
| Reaxys-RN | 3628192 |
| PubChem Substance ID | 87560875 |
| Merck Index(14) | 6845 |
| MDL編號 | MFCD00083192 |
產品規格
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
性質
| 熔點 | 151 °C(dec.) |
| 水溶性 | Insoluble |
| 溶解性（微溶於） | Ethanol, Methanol |
| 溶解性（不溶於） | Ether |
GHS
相關法規
| RTECS # | DD9087000 |
運輸資料
| HS編碼* | 2933.39-000 |
Application
Exosome research
Reference
- Effect of Proton Pump Inhibitor Pretreatment on Resistance of Solid Tumors to Cytotoxic Drugs
Application
最初に開発されたプロトンポンプ阻害剤 (PPI)，オメプラゾール
Omeprazole is the first proton pump inhibitor (PPI) that reduces gastric acid secretion. PPIs, such as omeprazole, lansoprazole [L0233], rabeprazole [R0115] and pantoprazole, are metabolized by cytochrome P 450 isoenzymes, 2C19 (CYP2C19) in the liver. The active (S)-enantiomer of omeprazole is esomeprazole. In additon, combinations of omeprazole as a PPI, amoxicillin [A2099], clarithromycin [C2220] and metronidazole [M0924] or another antibiotic have been reported to be effective in the treatment of Helicobacter pylori infection. Omeprazole is synthesized by the oxidation of omeprazole sulfide [O0437].
References
- Omeprazole. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in peptic ulcer disease and Zollinger-Ellison syndrome
- Omeprazole: the first proton pump inhibitor (a review)
- Omeprazole A review of its use in Helicobacter pylori infection, gastro-esophageal reflux disease and peptic ulcers induced by nonsteroidal anti-inflammatory drugs
- A proton-pump inhibitor expedition: the case histories of omeprazole and esomeprazole (a review)
- Pharmacogenomics of proton pump inhibitors (a review)
考研文獻
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