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CAS RN: 50-24-8 | Product Number: P0637
Prednisolone
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Purity: >98.0%(HPLC)
Synonyms:
- 11β,17α,21-Trihydroxypregna-1,4-diene-3,20-dione
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 1G |
€34.00
|
6 | 12 |
|
| 5G |
€106.00
|
2 | 3 |
|
| 25G |
€340.00
|
7 | 13 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | P0637 |
| Purity / Analysis Method | >98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__2__1H__2__8O__5 = 360.45 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| Packaging and Container | 1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 50-24-8 |
| Reaxys Registry Number | 1354103 |
| PubChem Substance ID | 87574796 |
| SDBS (AIST Spectral DB) | 10998 |
| Merck Index (14) | 7721 |
| MDL Number | MFCD00003649 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Specific rotation [a]20/D | +97.0 to +103.0 deg(C=1, Dioxane) |
| Solubility in Dioxane | almost transparency |
Properties (reference)
| Melting Point | 235 °C |
| Specific Rotation | 100° (C=1,Dioxane) |
| Solubility in water | Insoluble |
| Solubility (soluble in) | Methanol, Ethanol |
| Solubility (slightly sol. in) | Dioxane, Acetone |
| Solubility (insoluble in) | Ether |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H302 : Harmful if swallowed. H361 : Suspected of damaging fertility or the unborn child. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection/ hearing protection. P308 + P313 : IF exposed or concerned: Get medical advice/ attention. |
Related Laws:
| EC Number | 200-021-7 |
| RTECS# | TU4152000 |
Transport Information:
| HS Number | 2937210000 |
Application
Prednisolone: A Synthetic Adrenocortical Steroid Agent with Predominantly Glucocorticoid Properties
Prednisolone is a synthetic adrenocortical steroid agent with predominantly glucocorticoid properties, which is used for the treatment of a wide range of inflammatory and autoimmune conditions. It is the active hepatic metabolite of prednisone [P1276]. (The product is for research purpose only.)
References
- Goodman and Gilman's The Pharmacological Basis of Therapeutics, Twelfth Edition
- Pharmacokinetics and pharmacodynamics of systemically administered glucocorticoids (a review)
- Glucocorticoid action and the development of selective glucocorticoid receptor ligands (a review)
- Allergic and pseudoallergic reactions induced by glucocorticoids: A review
- Simple liquid chromatography method for the rapid simultaneous determination of prednisolone and cortisol in plasma and urine using hydrophilic lipophilic balanced solid phase extraction cartridges
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