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CAS RN: 26471-62-5 | Product Number: T0264
Tolylene Diisocyanate (2,4- ca. 80%, 2,6- ca. 20%)
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Purity: >98.0%(GC)
Synonyms:
- Toluene Diisocyanate (2,4- ca. 80%, 2,6- ca. 20%)
Product Documents:
| Size | Unit Price | Philadelphia, PA | Portland, OR | Japan* | Quantity |
Shipping Information
|
|---|---|---|---|---|---|---|
| 25G |
$30.00
|
1 | 1 | ≥60 |
|
|
| 500G |
$72.00
|
35 | ≥40 | ≥100 |
|
* Items in stock locally typically ship the same day of ordering. Items from Japan stock are able to ship from a US warehouse within 2 weeks after ordering. For additional estimated shipment times, please refer to the Shipping Simulation tool. Note: Excludes regulated items and items that ship on ice.
* To send your quote request for bulk quantities, please click on the "Request Quote" button. Please note that we cannot offer bulk quantities for some products.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
Supplemental Product Information:
[Handling Note]
This product may deposit some white solids during storage. Please use all of the material as soon as possible upon receiving it.
| Product Number | T0264 |
Purity / Analysis Method 
|
>98.0%(GC) |
| Molecular Formula / Molecular Weight | C__9H__6N__2O__2 = 174.16 |
| Physical State (20 deg.C) | Liquid |
| Storage Temperature
|
Refrigerated (0-10°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Light Sensitive,Moisture Sensitive,Heat Sensitive |
| CAS RN | 26471-62-5 |
| Reaxys Registry Number | 8188352 |
| PubChem Substance ID | 87576244 |
| MDL Number | MFCD01778251 |
Specifications
| Appearance | Colorless to Light yellow clear liquid |
| Purity(GC) | min. 98.0 %(total of isomer) |
Properties (reference)
| Melting Point | 14 °C |
| Boiling Point | 251 °C |
| Flash point | 137 °C |
| Specific Gravity (20/20) | 1.22 |
| Refractive Index | 1.57 |
| Solubility (miscible with) | Benzene, Ether, Acetone |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H330 : Fatal if inhaled. H315 : Causes skin irritation. H319 : Causes serious eye irritation. H370 : Causes damage to organs. H372 : Causes damage to organs through prolonged or repeated exposure. H317 : May cause an allergic skin reaction. H334 : May cause allergy or asthma symptoms or breathing difficulties if inhaled. H351 : Suspected of causing cancer. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P202 : Do not handle until all safety precautions have been read and understood. P260 : Do not breathe mist or vapours. P201 : Obtain special instructions before use. P271 : Use only outdoors or in a well-ventilated area. P264 : Wash skin thoroughly after handling. P284 : Wear respiratory protection. P272 : Contaminated work clothing must not be allowed out of the workplace. P280: Wear protective gloves, protective clothing, eye protection and face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P342 + P311 : If experiencing respiratory symptoms: Call a POISON CENTER/doctor. P308 + P313 : IF exposed or concerned: Get medical advice/ attention. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P333 + P313 : If skin irritation or rash occurs: Get medical advice/ attention. P304 + P340 + P310 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. Immediately call a POISON CENTER/doctor. P403 + P233 : Store in a well-ventilated place. Keep container tightly closed. P405 : Store locked up. |
Related Laws:
| RTECS# | NQ9490000 |
Transport Information:
| UN Number (DOT-AIR) | UN2078 |
| Class (DOT-AIR) | 6.1 |
| Packing Group (TCI-A) | II |
| HS Number | 2929.10.1500 |
Application
Reagent for airway hyperresponsiveness (asthma) model
References
- The development of an animal model for TDI asthma
- M. H. Karol, Bull. Eur. Physiopathol. Respir. 1987, 23, 571.
- An asthma model developed in the guinea pig by intranasal application of 2,4-toluene diisocyanate
- Importance of inflammatory and immune components in a mouse model of airway reactivity to toluene diisocyanate (TDI)
- A murine model of toluene diisocyanate-induced asthma can be treated with matrix metalloproteinase inhibitor
- Y. C. Lee, C. H. Song, H. B. Lee, J. L. Oh, Y. K. Rhee, H. S. Park, G. Y. Koh, J. Allergy Clin. Immunol. 2001, 108, 1021.
- Mesenchymal stem cell transfer suppresses airway remodeling in a toluene diisocyanate-induced murine asthma model
PubMed Literature
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Specifications
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Other Documents
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