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CAS RN: 490-46-0 | Product Number: E1226
(-)-Epicatechin
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Purity: >97.0%(HPLC)
Synonyms:
- (-)-cis-3,3',4',5,7-Pentahydroxyflavane
Product Documents:
| Size | Unit Price | Shanghai | Tianjin | Japan* |
|---|---|---|---|---|
| 1G |
¥490.00
|
37 | 2 | ≥100 |
| 5G |
¥1,990.00
|
1 | 1 | ≥100 |
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| Product Number | E1226 |
Purity / Analysis Method 
|
>97.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__1__5H__1__4O__6 = 290.27 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Refrigerated (0-10°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive,Heat Sensitive |
| Packaging and Container
|
1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 490-46-0 |
| Reaxys Registry Number | 92760 |
| PubChem Substance ID | 468591690 |
| MDL Number | MFCD00075648 |
Specifications
| Appearance | White to Light yellow to Light orange powder to crystal |
| Purity(HPLC) | min. 97.0 area% |
| Specific rotation [a]20/D | -56.0 to -64.0 deg(C=0.1, MeOH) |
Properties (reference)
| Melting Point | 240 °C(dec.) |
| Specific Rotation | -62° (C=0.1,MeOH) |
| Maximum Absorption Wavelength | 280 nm (MeOH) |
| Solubility (soluble in) | Methanol |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
Related Laws:
| RTECS# | K3745000 |
Transport Information:
| Customs Control Conditions (Q) |
Application
Efflux pump research
(-)-Epicatechin has been reported to inhibit efflux pump thereby decreasing the minimum inhibitory concentrations (MICs) of Isoniazid [I0138] against Mycobacterium.1)
（The product is for research purpose only.)
（The product is for research purpose only.)
Reference
- 1) Modulation of isoniazid susceptibility by flavonoids in Mycobacterium
- Determination of Tea Components with Antioxidant Activity
- Metabolism of green tea catechins: an overview
- Green tea extract: Chemistry, antioxidant properties and food applications - A review
- Antiviral effect of catechins in green tea on influenza virus
- Green Tea: Nature's Defense against Malignancies (a review)
- Biological functions of epicatechin: Plant cell to human cell health (a review)
- (-)-Epicatechin mediates beneficial effects of flavanol-rich cocoa on vascular function in humans
- Metabolism of green tea catechins: an overview
- Dietary flavonoids: Role of (-)-epicatechin and related procyanidins in cell signaling (a review)
Application
(-)-Epicatechin: A Components of Green Tea with a Variety of Biological Activities
(-)-Epicatechin and (-)-epicatechin gallate [E0890] are major components of green tea which is the most popular beverages worldwide. It has been reported that they possess a variety of biological activities, including antioxidant, anti-inflammatory, antiviral and anti-cancerous properties. (The product is for research purpose only.)
References
Application
(-)-Epicatechin: An Antioxidant Flavonoid with Many Bioactive Properties
(-)-Epicatechin is a flavan-3-ol, an antioxidant flavonoid that is present in green teas, red wine, cocoa products, and many fruits, such as apples. It has demonstrated strong antioxidative, anti-inflammatory and anti-cancerous properties. (The product is for research purpose only.)
References
Documents
Product Articles
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