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CAS RN: 636582-62-2 | Product Number: M3660
Mosapride Citrate Dihydrate
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Purity: >95.0%(HPLC)(qNMR)
Synonyms:
- 4-Amino-5-chloro-2-ethoxy-N-[[4-(4-fluorobenzyl)-2-morpholinyl]methyl]benzamide Citric Acid Dihydrate
- 4-Amino-5-chloro-2-ethoxy-N-[(4-(4-fluorobenzyl)morpholin-2-yl)methyl]benzamide 2-Hydroxypropane-1,2,3-tricarboxylic Acid Dihydrate
Product Documents:
| Size | Unit Price | Shanghai | Tianjin | Japan* |
|---|---|---|---|---|
| 10MG |
¥1,390.00
|
Contact Us | Contact Us | ≥80 |
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| Product Number | M3660 |
Purity / Analysis Method 
|
>95.0%(HPLC)(qNMR) |
| Molecular Formula / Molecular Weight | C__2__1H__2__5ClFN__3O__3·C__6H__8O__7·2H__2O = 650.05 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive |
| CAS RN | 636582-62-2 |
| Reaxys Registry Number | 30656545 |
| MDL Number | MFCD0874415 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 95.0 area% |
| Purity(qNMR) | min. 95.0 % |
| Water | 5.0 to 6.5 % |
| NMR | confirm to structure |
Properties (reference)
| Solubility in water | Insoluble |
| Solubility (slightly sol. in) | Methanol |
GHS
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| Customs Control Conditions (Q) |
Application
Mosapride Citrate: A Selective 5-HT4 Receptor Agonist
Mosapride citrate (AS-4370) is a selective 5-HT4 receptor agonist with documented stimulatory effects on gastric and colonic motility with no affinity for 5-HT1 and 5-HT2 receptors. Mosapride is also active through its main metabolite, the de-4-fluorobenzyl metabolite (M-1), which is a 5-HT3 agonist. In addition, mosapride does not bind to D2 dopaminergic receptor. (The product is for research use only.)
References
- AS-4370, a new gastrokinetic agent, enhances upper gastrointestinal motor activity in conscious dogs
- Effects of Mosapride Citrate, a 5-HT4 Receptor Agonist, on Colonic Motility in Conscious Guinea Pigs
- The effect of mosapride, a novel prokinetic, on acid reflux variables in patients with gastro-esophageal reflux disease
Product Documents (Note: Some products will not have analytical charts available.)
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