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CAS RN: 1423-26-3 | Product Number: T1793
3-(Trifluoromethyl)phenylboronic Acid (contains varying amounts of Anhydride)
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Purity:
Synonyms:
- α,α,α-Trifluoro-m-tolueneboronic Acid (contains varying amounts of Anhydride)
- α,α,α-Trifluoro-m-tolylboronic Acid (contains varying amounts of Anhydride)
Product Documents:
| Size | Unit Price | Shanghai | Tianjin | Japan* |
|---|---|---|---|---|
| 1G |
¥70.00
|
5 | 8 | ≥100 |
| 5G |
¥140.00
|
2 | 11 | ≥60 |
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| Product Number | T1793 |
| Molecular Formula / Molecular Weight | C__7H__6BF__3O__2 = 189.93 |
| Physical State (20 deg.C) | Solid |
Storage Temperature 
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| Packaging and Container
|
1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 1423-26-3 |
| Reaxys Registry Number | 6084746 |
| PubChem Substance ID | 87577526 |
| MDL Number | MFCD00151854 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(Neutralization titration) | 97.0 to 111.0 % |
Properties (reference)
| Solubility (slightly sol. in) | Methanol |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
Related Laws:
Transport Information:
| Customs Control Conditions (Q) |
Application
AmpC β-lactamase inhibitor
The primary resistance mechanism of microbes to β-lactam antibiotics is hydrolysis of the antibiotics by β-lactamase.1) 3-(Trifluoromethyl)phenylboronic acid is one of boronic acid compounds having β-lactamase (AmpC) inhibition activity (Ki = 1.1 ± 0.3 μM).2)
References
- β-Lactamases and β-Lactamase Inhibitors in the 21st Century
- Structure-Based Enhancement of Boronic Acid-Based Inhibitors of AmpC β-Lactamase
PubMed Literature
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Specifications
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