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CAS RN: 3902-71-4 | Product Number: T2267


Purity: >98.0%(HPLC)
  • TMP
  • 2,5,9-Trimethylfuro[3,2-g]benzopyran-7-one
  • 4,5',8-Trimethylpsoralen
  • Trisoralen
2   Contact Us ≥20 
1   2   ≥20 

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Product Number T2267
Purity / Analysis Method >98.0%(HPLC)
Molecular Formula / Molecular Weight C__1__4H__1__2O__3 = 228.25  
Physical State (20 deg.C) Solid
Condition to Avoid Light Sensitive
CAS RN 3902-71-4
Reaxys Registry Number 221723
PubChem Substance ID 87558287
Merck Index (14) 9735
Appearance White to Light yellow powder to crystal
Purity(HPLC) min. 98.0 area%
Properties (reference)
Melting Point 234 °C
Solubility in water Insoluble
Solubility (slightly sol. in) Chloroform,Alcohol
Pictogram Pictogram
Signal Word Danger
Hazard Statements H314 : Causes severe skin burns and eye damage.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P260 : Do not breathe dusts or mists.
P264 : Wash skin thoroughly after handling.
P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection.
P303 + P361 + P353 : IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/shower.
P301 + P330 + P331 : IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P363 : Wash contaminated clothing before reuse.
P304 + P340 + P310 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. Immediately call a POISON CENTER/doctor.
P305 + P351 + P338 + P310 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER/doctor.
P405 : Store locked up.
Related Laws:
RTECS# LV1576000
Transport Information:
UN Number UN1759
Class 8
Packing Group III
Customs Control Conditions (Q)
4,5',8-Trimethylpsoralen: A Photosensitizer in Combination with UV-A irradiation, called PUVA

5-Methoxypsoralen (5-MOP) [B2840], 8-methoxypsoralen (8-MOP) [X0009] and 4,5',8-trimethylpsoralen are naturally occurring linear psoralens (furocoumarins). They have been successfully used as photosensitizers in combination with UV-A irradiation which is called the psoralen-based PUVA (psoralen + UV-A) to manage dermatological diseases, such as psoriasis, vitiligo and cancer. Reportedly, the most important mechanism implies the [2 + 2] cycloaddition photoreaction of psoralen and a DNA pyrimidine nucleobase. The formation of psoralen-pyrimidine adducts prevents the division of the injured cells. In another photoreaction, the activated psoralen can transfer energy to molecular oxygen to generate reactive radicals or excited singlet oxygen which becomes prone to damage the membrane of the harmed cell. Furthermore, 4,5',8-trimethylpsoralen-conjugated oligonucleotides have been used in the study of photo-cross-linking with target oligonucleotides. (The product is for research purpose only.)


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