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CAS RN: 40828-46-4 | Product Number: U0138
Suprofen
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Purity: >98.0%(GC)
Synonyms:
- 2-[4-(2-Thienylcarbonyl)phenyl]propanoic Acid
- 2-[4-(Thiophene-2-carbonyl)phenyl]propanoic Acid
- α-Methyl-4-(2-thienylcarbonyl)benzeneacetic Acid
Product Documents:
| Size | Unit Price | Shanghai | Tianjin | Japan* |
|---|---|---|---|---|
| 25MG |
¥250.00
|
2 | Contact Us | 18 |
| 100MG |
¥990.00
|
1 | 1 | 19 |
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| Product Number | U0138 |
Purity / Analysis Method 
|
>98.0%(GC) |
| Molecular Formula / Molecular Weight | C__1__4H__1__2O__3S = 260.31 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| Packaging and Container
|
100MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 40828-46-4 |
| Reaxys Registry Number | 1430606 |
| PubChem Substance ID | 468593092 |
| MDL Number | MFCD00079572 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(GC) | min. 98.0 % |
| Melting point | 121.0 to 125.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 123 °C |
| Maximum Absorption Wavelength | 289 nm (CH__3CN) |
| Solubility (soluble in) | Ethanol, Methanol |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H301 : Toxic if swallowed. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P405 : Store locked up. |
Related Laws:
| RTECS# | MU6647000 |
Transport Information:
| UN Number | UN2811 |
| Class | 6.1 |
| Packing Group | III |
| Customs Control Conditions (Q) |
Application
Suprofen: A Dual COX-1/COX-2 Inhibitor
Suprofen is a nonsteroidal anti-inflammatory 2-arylpropionic acid, and binds to the cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) isozymes, preventing the synthesis of prostaglandins and reducing the inflammatory response. In clinical, suprofen is used as a non-steroidal anti-inflammatory analgesic and antipyretic, and a nonsteroidal anti-inflammatory drug (NSAID). In addition, certain NSAIDs (including suprofen) have been also reported to be associated with photosensitive reactions. (The product is for research purpose only.)
References
- Suprofen. A review of its pharmacodynamic and pharmacokinetic properties, and analgesic efficacy
- Photoreactivity of the nonsteroidal anti-inflammatory 2-arylpropionic acids with photosensitizing side effects (a review)
Product Documents (Note: Some products will not have analytical charts available.)
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