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CAS RN: 4291-63-8 | Product Number: C2499

Cladribine


Purity: >98.0%(HPLC)
Synonyms:
  • 2-Chloro-2'-deoxyadenosine
  • 2-Chloro-9-(2-deoxy-β-D-arabinofuranosyl)adenine
  • CdA
Documents:
50MG
₹24,800.00
4   ≥40 

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Product Number C2499
Purity / Analysis Method >98.0%(HPLC)
Molecular Formula / Molecular Weight C__1__0H__1__2ClN__5O__3 = 285.69 
Physical State (20 deg.C) Solid
Storage Temperature Refrigerated (0-10°C)
Condition to Avoid Heat Sensitive
Packaging and Container 50MG-Glass Bottle with Plastic Insert (View image)
CAS RN 4291-63-8
Reaxys Registry Number 624220
PubChem Substance ID 160871152
Merck Index (14) 2337
MDL Number

MFCD00153939

Specifications
Appearance White to Almost white powder to crystal
Purity(HPLC) min. 98.0 area%
Properties (reference)
Melting Point 220 °C
Maximum Absorption Wavelength 265(EtOH aq.) nm
GHS
Related Laws:
RTECS# AU7357560
Transport Information:
Application
Studies on Chronic Lymphocytic Leukemia Cells

References

  • Deoxyadenosine analogs induce programmed cell death in chronic lymphocytic leukemia cells by damaging the DNA and by directly affecting the mitochondria
    • D. Genini, S. Adachi, Q. Chao, D. W. Rose, C. J. Carrera, H. B. Cottam, D. A. Carson, L. M. Leoni, Blood 2000, 96, 3537.
  • Induction of apoptotic cell death in chronic lymphocytic leukemia by 2-chloro-2'-deoxyadenosine and 9-β-D-arabinosyl-2-fluoroadenine
    • L. E. Robertson, S. Chubb, R. E. Meyn, M. Story, R. Ford, W. N. Hittelman, W. Plunkett, Blood 1993, 81, 143.
  • Specific toxicity of 2-chlorodeoxyadenosine toward resting and proliferating human lymphocytes
    • D. A. Carson, D. B. Wasson, R. Taetle, A. Yu, Blood 1983, 62, 737.


PubMed Literature


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