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CAS RN: 16980-89-5 | Product Number: D4228

Bucladesine Sodium Salt

Purity: >95.0%(HPLC)(qNMR)

Synonyms:

N⁶,2'-O-Dibutyryladenosine 3',5'-Cyclic Monophosphate Sodium Salt
Dibutyryl cAMP Sodium Salt

Documents:

SDS | Specifications | C of A & Other Certificates | Analytical Charts

Size	Unit Price	Hyderabad	Japan*	Quantity
25MG	₹7,600.00	Contact Us	≥100

*Upon orders receipt, Hyderabad stocks will be dispatched on the same day.
*Items available in Japan warehouse will be dispatched in 10-12 working days.
*INR price is exclusive of domestic taxes applicable.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.

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General Information plus

Product Number	D4228
Purity / Analysis Method	>95.0%(HPLC)(qNMR)
Molecular Formula / Molecular Weight	C__1__8H__2__3N__5NaO__8P = 491.37
Physical State (20 deg.C)	Solid
Storage Temperature	Frozen (-20°C)
Condition to Avoid	Heat Sensitive
CAS RN	16980-89-5
Related CAS RN	362-74-3
PubChem Substance ID	354335826
Merck Index (14)	1463
MDL Number	MFCD00005843

Specifications & Properties plus

Specifications

Appearance	White to Almost white powder to crystal
Purity(HPLC)	min. 95.0 area%
Purity(qNMR)	min. 95.0 %
NMR	confirm to structure

Properties (reference)

Solubility (insoluble in)

Acetone, Ether

Safety & Regulations plus

GHS

Related Laws:

RTECS#

ES5055500

Transport Information:

Applications plus

Application

Bucladesine, A Cyclic Adenosine Monophosphate (cAMP) Agalogue

Bucladesine or Dibutyryl cAMP is a stabilized cyclic adenosine monophosphate (cAMP) [A2381, A2112] analogue. It is a cell-permeable, cyclic nucleotide derivative that mimics the action of cAMP. In addition, it is an inhibitor of cyclic nucleotide phosphodiesterase.

References

Preparation of separate astroglial and oligodendroglial cell cultures from rat cerebral tissue
- K. D. McCarthy, J. de Vellis, J. Cell Biol. 1980, 85, 890.
Hormonal induction of differentiation in teratocarcinoma stem cells: generation of parietal endoderm by retinoic acid and dibutyryl cAMP
- S. Strickland, K. K. Smith, K. R. Marotti, Cell 1980, 21, 347.
cAMP analogs promote survival and neurite outgrowth in cultures of rat sympathetic and sensory neurons independently of nerve growth factor
- R. E. Rydel, L. A. Greene, Proc. Natl. Acad. Sci. U.S.A. 1988, 85, 1257.
Up-regulation of monocytic IL-10 by tumor necrosis factor-α and cAMP elevating drugs
- C. Platzer, Ch. Meisel, K. Vogt, M. Platzer, H.-D. Volk, Int. Immunol. 1995, 7, 517.
Rat oocyte maturation in vitro: Relief of cyclic AMP inhibition by gonadotropins
- N. Dekel, W. H. Beers, Proc. Natl. Acad. Sci. U.S.A. 1978, 75, 4369.

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CAS RN: 16980-89-5 | Product Number: D4228