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CAS RN: 107007-99-8 | Product Number: G0401

Granisetron Hydrochloride


Purity: >98.0%(T)(HPLC)
Synonyms:
  • 1-Methyl-N-[(3-endo)-9-methyl-9-azabicyclo[3.3.1]non-3-yl]-1H-indazole-3-carboxamide Hydrochloride
Documents:
200MG
₹3,200
1   4  
1G
₹9,700
1   5  

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Product Number G0401
Purity / Analysis Method >98.0%(T)(HPLC)
Molecular Formula / Molecular Weight C__1__8H__2__4N__4O·HCl = 348.88  
Physical State (20 deg.C) Solid
CAS RN 107007-99-8
Related CAS RN 109889-09-0
Reaxys Registry Number 3640184
PubChem Substance ID 172089139
Merck Index (14) 4536
MDL Number

MFCD01747034

Specifications
Appearance White to Almost white powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(Nonaqueous Titration) min. 98.0 %
Properties (reference)
Melting Point 292 °C(dec.)
GHS
Pictogram Pictogram
Signal Word Warning
Hazard Statements H302 : Harmful if swallowed.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P270 : Do not eat, drink or smoke when using this product.
P264 : Wash skin thoroughly after handling.
P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth.
Related Laws:
RTECS# NK7882200
Transport Information:
Application
Granisetron Hydrochloride: A Potent and Highly Selective 5-Hydroxytryptamine 3 (5-HT3) Receptor Antagonist

Granisetron hydrochloride is a potent and highly selective 5-hydroxytryptamine 3 (5-HT3) receptor antagonist that has little or no affinity for other serotonin receptors, including 5-HT1; 5-HT1A; 5-HT1B/C; 5-HT2; for α1-, α2- or β-adrenergic receptors; for dopamine-D2; or for histamine-H1; benzodiazepine; picrotoxin or opioid receptors. 5-HT3 receptors are located peripherally on vagal nerve terminals and centrally in the chemoreceptor trigger zone (CTZ) of the area postrema, known as the emetic center of the brain. Therefore, granisetron is used for the prevention of chemotherapy-induced nausea and vomiting. (The product is for research purpose only.)

References


PubMed Literature


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