CAS RN: 190791-29-8 | Product Number: L0336
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|Purity / Analysis Method||>98.0%(HPLC)|
|Molecular Formula / Molecular Weight||C__2__8H__3__1NO__2·C__4H__6O__6 = 563.65|
|Physical State (20 deg.C)||Solid|
|Store Under Inert Gas||Store under inert gas|
|Condition to Avoid||Air Sensitive,Hygroscopic,Heat Sensitive|
|Reaxys Registry Number||14771789|
|Appearance||White to Almost white powder to crystal|
|Purity(HPLC)||min. 98.0 area%|
|Melting Point||185 °C(dec.)|
- 1) Effects of CP-336,156, a new, nonsteroidal estrogen agonist/antagonist, on bone, serum cholesterol, uterus, and body composition in rat models
- 2) Discovery and Preclinical Pharmacology of a Novel, Potent, Nonsteroidal Estrogen Receptor Agonist/Antagonist, CP-336156, a Diaryltetrahydronaphthalene
- R. L. Rosati, P. Da Silva Jardine, K. O. Cameron, D. D. Thompson, H. Z. Ke, S. M. Toler, T. A. Brown, L. C. Pan, C. F. Ebbinghaus, A. R. Reinhold, N. C. Elliott, B. N. Newhouse, C. M. Tjoa, P. M. Sweetnam, M. J. Cole, M. W. Arriola, J. W. Gauthier, D. T. Crawford, D. F. Nickerson, C. M. Pirie, H. Qi, H. A. Simmons, G. T. Tkalcevic, J. Med. Chem. 1998, 41, 2928.
- 3) Lasofoxifene (CP-336,156), a selective estrogen receptor modulator, prevents bone loss induced by aging and orchidectomy in the adult rat
- 4) Lasofoxifene: a third-generation selective estrogen receptor modulator for the prevention and treatment of osteoporosis (a review)
- 5) Preventive therapy for breast cancer: a consensus statement (a review)
- 6) The discovery and development of selective estrogen receptor modulators (SERMs) for clinical practice (a review)
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