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CAS RN: 53797-35-6 | Product Number: R0194
Ribostamycin Sulfate
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Purity: >90.0%(N)
Synonyms:
Product Documents:
| Size | Unit Price | Hyderabad | Japan* | Quantity |
|---|---|---|---|---|
| 1G |
₹8,600.00
|
Contact Us | 1 |
|
*Upon orders receipt, Hyderabad stocks will be dispatched on the same day.
*Items available in Japan warehouse will be dispatched in 10-12 working days.
*INR price is exclusive of domestic taxes applicable.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
| Product Number | R0194 |
Purity / Analysis Method 
|
>90.0%(N) |
| Molecular Formula / Molecular Weight | C__1__7H__3__4N__4O__1__0·xH__2SO__4 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
| CAS RN | 53797-35-6 |
| Related CAS RN
|
25546-65-0 |
| Reaxys Registry Number | 8820400 |
| PubChem Substance ID | 354335294 |
| Merck Index (14) | 8206 |
| MDL Number | MFCD00057496 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 97.0 area% |
| Specific rotation [a]20/D | +41.0 to +45.0 deg(C=1,H2O) |
| Drying loss | max. 5.0 % |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 180 °C |
| Specific Rotation | 44° (C=1,H2O) |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H360 : May damage fertility or the unborn child. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection. P308 + P313 : IF exposed or concerned: Get medical advice/ attention. P405 : Store locked up. |
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Application
Ribostamycin Sulfate: A Broad-Spectrum Aminoglycoside Antibiotic
Ribostamycin sulfate (SF-733) is a broad-spectrum aminoglycoside antibiotic isolated from Streptomyces ribosifidicus. It has activity against both Gram-negative and Gram-positive bacteria but has no activity against yeasts or fungi. Ribostamycin irreversibly binds to the 30S subunit (16S rRNA) of the bacterial ribosome as with any other aminoglycoside antibiotics, and then it inhibits bacterial growth by inhibiting protein synthesis. (The product is for research purpose only.)
References
- Antibiotic SF-733, a new antibiotic. I. Taxonomy, isolation, and characterization
- In vitro activity of mezlocillin, meropenem, aztreonam, vancomycin, teicoplanin, ribostamycin, and fusidic acid against Borrelia burgdorferi
- Ribostamycin inhibits the chaperone activity of protein disulfide isomerase
- Binding of neomycin-class aminoglycoside antibiotics to the A-site of 16 S rRNA
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Specifications
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