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CAS RN: 123441-03-2 | Product Number: R0250

Rivastigmine


Purity: >98.0%(HPLC)
Synonyms:
  • (S)-3-[1-(Dimethylamino)ethyl]phenyl Ethyl(methyl)carbamate
  • Ethylmethylcarbamic Acid 3-[(S)-1-(Dimethylamino)ethyl]phenyl Ester
Documents:
1G
₹16,200.00
2   ≥40 

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Product Number R0250
Purity / Analysis Method >98.0%(HPLC)
Molecular Formula / Molecular Weight C__1__4H__2__2N__2O__2 = 250.34 
Physical State (20 deg.C) Liquid
Storage Temperature Refrigerated (0-10°C)
Store Under Inert Gas Store under inert gas
Condition to Avoid Air Sensitive,Heat Sensitive
CAS RN 123441-03-2
Reaxys Registry Number 7875788
PubChem Substance ID 468592798
MDL Number

MFCD00871496

Specifications
Appearance Colorless to Light yellow clear liquid
Purity(HPLC) min. 98.0 area%
Specific rotation -31.0 to -35.0deg (C=1, ethanol)
NMR confirm to structure
Properties (reference)
Boiling Point 135 °C/0.26 mmHg
Flash point 145.0 °C
Specific Gravity (20/20) 1.03
Solubility in water Slightly soluble
Solubility (miscible with) Methanol, Ethanol
GHS
Pictogram Pictogram
Signal Word Danger
Hazard Statements H301 : Toxic if swallowed.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P270 : Do not eat, drink or smoke when using this product.
P264 : Wash skin thoroughly after handling.
P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth.
P405 : Store locked up.
Related Laws:
RTECS# FA9546000
Transport Information:
UN Number UN2810
Class 6.1
Packing Group III
Application
Rivastigmine: A Dual Inhibitor of Acetylcholinesterase (AChE) and Butyrylcholinesterase (BuChE)

Rivastigmine is an inhibitor of two cholinesterase enzymes, acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE). Rivastigmine activates central cholinergic nervous system by increasing the concentration of acetylcholine (ACh) in brain through reversible inhibition of its hydrolysis by AChE and BuChE. For comparison, another cholinesterase inhibitor, donepezil hydrochloride [D4099] shows high selectivity for AChE over BuChE. In clinical, its tartrate [R0093] is used for the treatment of Alzheimer’s disease. (The product is for research purpose only.)

References


Documents (Note: Some products will not have analytical charts available.)
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