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CAS RN: 163521-08-2 | Product Number: V0149
Vilazodone Hydrochloride
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Purity: >98.0%(HPLC)
Synonyms:
- 5-[4-[4-(5-Cyano-1H-indol-3-yl)butyl]piperazin-1-yl]benzofuran-2-carboxamide Hydrochloride
Documents:
| Size | Unit Price | Hyderabad | Japan* | Quantity |
|---|---|---|---|---|
| 50MG |
₹8,600.00
|
Contact Us | 1 |
|
| 200MG |
₹14,800.00
|
Contact Us | 8 |
|
*Upon orders receipt, Hyderabad stocks will be dispatched on the same day.
*Items available in Japan warehouse will be dispatched in 10-12 working days.
*INR price is exclusive of domestic taxes applicable.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
| Product Number | V0149 |
| Purity / Analysis Method | >98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__2__6H__2__7N__5O__2·HCl = 477.99 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | -20°C |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Hygroscopic,Heat Sensitive |
| CAS RN | 163521-08-2 |
| Reaxys Registry Number | 9830698 |
| PubChem Substance ID | 354335070 |
| MDL Number | MFCD00940014 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
Properties (reference)
| Melting Point | 279 °C |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H302 + H312 + H332 : Harmful if swallowed, in contact with skin or if inhaled. H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P261 : Avoid breathing dust/ fume/ gas/ mist/ vapors/ spray. P270 : Do not eat, drink or smoke when using this product. P271 : Use only outdoors or in a well-ventilated area. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. P302 + P352 + P312 : IF ON SKIN: Wash with plenty of water.Call a POISON CENTER/doctor if you feel unwell. P304 + P340 + P312 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. Call a POISON CENTER/doctor if you feel unwell. |
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Application
Vilazodone Hydrochloride: A Selective Serotonin Reuptake Inhibitor (SSRI) with 5-HT1A Receptor Partial Agonist Activity
Vilazodone hydrochloride (EMD 68843) is a selective serotonin reuptake inhibitor (SSRI) with 5-HT1A receptor partial agonist activity. Vilazodone binds with high affinity to the serotonin reuptake site, but not to the norepinephrine or dopamine reuptake sites. Vilazodone is used as a dual-acting serotonergic antidepressant. Although the exact mechanism is unknown, but is though to be related to its enhancement of serotonergic activity in the central nervous system (CNS) through selective inhibition of serotonin reuptake. (The product is for research purpose only.)
References
- Behavioral and neurochemical effects of 5-{4-[4-((5-cyano-3-indolyl)butyl)butyl]-1-piperazinyl}benzofuran-2-carboxamide (EMD 68843): a combined selective inhibitor of serotonin reuptake and 5-hydroxytryptamine1A receptor partial agonist
- Synthesis and Structure-Activity Relationship in a Class of Indolebutylpiperazines as Dual 5-HT1A Receptor Agonists and Serotonin Reuptake Inhibitors
- Neurochemical evaluation of the novel 5-HT1A receptor partial agonist/serotonin reuptake inhibitor, vilazodone
- Vilazodone: A 5-HT1A receptor agonist/serotonin transporter inhibitor for the treatment of affective disorders (a review)
- Selective serotonin reuptake inhibitors (SSRIs): therapeutic drug monitoring and pharmacological interactions (a review)
- Identification of hydrolytic and isomeric N-oxide degradants of vilazodone by on line LC-ESI-MS/MS and APCI-MS
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