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CAS RN: 3685-84-5 | Product Number: M2460
Meclofenoxate Hydrochloride
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Purity: >98.0%(T)
Synonyms:
- 2-(Dimethylamino)ethyl 2-(4-Chlorophenoxy)acetate Hydrochloride
- 2-(4-Chlorophenoxy)acetic Acid 2-(Dimethylamino)ethyl Ester Hydrochloride
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 1G |
₩35,100
|
18 | 13 | Contact Us | |
| 5G |
₩93,600
|
5 | 0 | Contact Us |
* Please contact our distributor of SEJIN CI Co., Ltd.
if you would like to purchase TCI products. The above prices do not include freight cost, customs charge and other charges to the destination. SEJIN CI Co., Ltd. (Phone: 02-2655-2480 / email:
sales@sejinci.co.kr)
* The storage conditions are subject to change without notice.
* The storage conditions are subject to change without notice.
| Product Number | M2460 |
Purity / Analysis Method 
|
>98.0%(T) |
| Molecular Formula / Molecular Weight | C__1__2H__1__6ClNO__3·HCl = 294.17 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Refrigerated (0-10°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Hygroscopic,Heat Sensitive |
| Packaging and Container
|
1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 3685-84-5 |
| Related CAS RN
|
51-68-3 |
| Reaxys Registry Number | 3637332 |
| PubChem Substance ID | 253661831 |
| Merck Index (14) | 5780 |
| MDL Number | MFCD00012533 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 97.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Melting point | 137.0 to 142.0 °C |
Properties (reference)
| Melting Point | 139 °C |
| Solubility (soluble in) | Acetone |
| Solubility (insoluble in) | Benzene, Chloroform, Ether |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H302 : Harmful if swallowed. H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
Related Laws:
| RTECS# | AG0440000 |
Transport Information:
| H.S.code* | 2922.19-000 |
Application
Meclofenoxate Hydrochloride: A Compound Acting as a Precursor of Acetylcholine and a Free-Radical Scavenger
Meclofenoxate, also called centrophenoxine, is the ester made from 4-chlorophenoxyacetic acid [C0250] and 2-(dimethylamino)ethanol (also called dimethylaminoethanol or DMAE) [D0649]. It is reported that meclofenoxate increases the DMAE levels in the brain. DMAE is a precursor of acetylcholine, an important neurotransmitter in the brain. Therefore, meclofenoxate is widely recognized as a nootropic enhancer. In addition, DMAE is also reported as a free-radical scavenger and an antioxidant. (The product is for research purpose only.)
References
- Increases in choline levels in rat brain elicited by meclofenoxate
- On the role of intracellular physicochemistry in quantitative gene expression during aging and the effect of centrophenoxine. A review
- Changes in brain biogenic monoamines induced by the nootropic drugs adafenoxate and meclofenoxate and citicholine (experiments on rats)
- Age-related decline in multiple unit action potentials of CA3 region of rat hippocampus: correlation with lipid peroxidation and lipofuscin concentration and the effect of centrophenoxine
- Effect of centrophenoxine against rotenone-induced oxidative stress in an animal model of Parkinson's disease
- Kinetic study on the degradation of meclophenoxate hydrochloride in alkaline aqueous solutions by high performance liquid chromatography
- A Simple and Sensitive HPLC Method for Quantification of the Metabolin of Meclofenoxate in Human Plasma
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