text.skipToContent text.skipToNavigation

Maximum quantity allowed is 999

Please select the quantity

Corey-Fuchs Reaction

The Corey-Fuchs reaction is a two-step reaction sequence used to convert aldehydes into terminal alkynes. The intermediate 1,1-dibromoalkene is produced from aldehydes, triphenylphosphine and carbon tetrabromide during the reaction sequence and can be isolated. This is then converted to the alkyne following the addition of a strong base such as butyllithium.
Reagents:
Carbon tetrabromide, Triphenylphosphine, Butyllithium
Reactants:
Aldehydes
Products:
Terminal alkynes
Scheme:

Corey-Fuchs reaction

Original literature:
Review literature: