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TCI Chemistry News

August 2023

TCI offers an extensive catalog of over 30,000 high quality organic reagents suitable for benchtop-to-bulk chemistry. This issue covers our chemistry topics as follows:


HPMC Capsule Reagents

HPMC Capsule Reagents

TCI offers hydroxypropyl methylcellulose (HPMC) encapsulated reagents; reagent for amide formation reactions (condensation reactions) [R0274], reagent for Suzuki coupling reactions [R0275], and reagent for metallophotoredox cross-coupling reactions [R0273]. Using these encapsulated reagents, you can conduct reactions immediately by adding the capsules to the solution of the starting material without weighing the reaction reagents. Additionally, a reaction-accelerating effect is expected due to the construction of a reaction field in water by HPMC. Chiral Phosphine Ligands Skewphos Derivatives

Chiral Phosphine Ligands Skewphos Derivatives

(2S,4S)-2,4-Bis[bis(4-dimethylaminophenyl)phosphino]pentane [P2852], (2R,4R)-2,4-bis[bis(4-dimethylaminophenyl)phosphino]pentane [P2853] and (2S,4S)-2,4-bis[bis(3,5-dimethylphenyl)phosphino]pentane [P2854] are asymmetric phosphine ligands bearing flexible skeletons. Each ligand possesses different reactivity and selectivity depending on the electron density and steric hindrance of the aryl groups. Construction of the Terminal Alkyne Using Ohira-Bestmann Reagent

TCI Practical Example: Construction of the Terminal Alkyne Using Ohira-Bestmann Reagent

We are proud to present the synthesis of 1-dodecyne utilizing Ohira-Bestmann reagent [D3546] and undecanal. Bromination Reaction Using N-Bromosuccinimide

TCI Practical Example: Bromination Reaction Using N-Bromosuccinimide

TCI introduces the regioselective bromination reaction of 2-methylbenzo[b]thiophene by using N-bromosuccinimide (= NBS) [B0656].

Upcoming Events

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August 27- September 1, 2023
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