Maintenance Notice (10:30 PM June 7 - 2:00 AM June 8, 2025 UTC): This website is scheduled to be unavailable due to maintenance. We appreciate your patience and understanding.
Product Document Searching Made Easy by 2D Code! | TCI Chemistry News June 2025 | [Product Highlights] Benzoquinone Derivative Useful for... | Various analytical charts can be searched on each product detail page and Product Document Search (The kinds of analytical charts differ by product)
Maximum quantity allowed is 999
请选择数量
CAS RN: 5142-23-4 | 产品编码: M2518
3-Methyladenine
×
![]()
×
| 产品编码 | M2518 |
| 分子式/分子量 | C__6H__7N__5 = 149.16 |
| 外观与形状（20°C） | 固体 |
| 储存温度 | 室温 (15°C以下阴凉干燥处) |
| 包装和容器 | 1G-Glass Bottle with Plastic Insert （查看图片）, 200MG-Glass Bottle with Plastic Insert （查看图片） |
| CAS RN | 5142-23-4 |
| Reaxys-RN | 146087 |
| PubChem物质ID | 253660841 |
| MDL编号 | MFCD00010531 |
技术规格
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 97.0 % |
物性（参考值）
| 熔点 | 300 °C(dec.) |
GHS
| 象形图 |
|
| 信号词 | Warning |
| 危险性说明 | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| 防范说明 | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
相关法规
| RTECS# | AU6520000 |
运输信息
| HS编码* | 2933.99-000 |
应用
3-Methyladenine (3-MA): A PI3K inhibitor - An Autophagy Inhibitor
3-Methyladenine (3-MA) inhibits phosphoinositide 3-kinases (PI3K) such as wortmannin [W0007], and is generally used as an inhibitor of autophagy which is an intracellular degradation system that delivers cytoplasmic constituents to the lysosome. Recently, in addition to its role in autophagy, 3-MA has been implicated in cancer research. (The product is for research purpose only.)
References
- 3-Methyladenine: Specific inhibitor of autophagic/lysosomal protein degradation in isolated rat hepatocytes
- 3-Methyladenine, an inhibitor of autophagy, has multiple effects on metabolism
- 3-Methyladenine inhibits autophagy in tobacco culture cells under sucrose starvation conditions
- Inhibition of autophagy augments 5-fluorouracil chemotherapy in human colon cancer in vitro and in vivo model
- Dual Role of 3-Methyladenine in Modulation of Autophagy via Different Temporal Patterns of Inhibition on Class I and III Phosphoinositide 3-Kinase
- Inhibition of autophagy by 3-MA potentiates cisplatin-induced apoptosis in esophageal squamous cell carcinoma cells
参考文献
技术文章
产品文档 (部分产品的分析图谱无法提供，敬请谅解。)