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CAS RN: 22465-48-1 | Product Number: H1542

Hydroxocobalamin Acetate


Purity: >90.0%(HPLC)
Synonyms:
  • Vitamin B12a Acetate
Documents:
1G
$223.00
4   1   ≥100 
5G
$772.00
4   1   17  

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Product Number H1542
Purity / Analysis Method >90.0%(HPLC)
Molecular Formula / Molecular Weight C__6__4H__9__1CoN__1__3O__1__6P = 1,388.41 
Physical State (20 deg.C) Solid
Storage Temperature Refrigerated (0-10°C)
Store Under Inert Gas Store under inert gas
Condition to Avoid Air Sensitive,Heat Sensitive
Packaging and Container 1G-Glass Bottle with Plastic Insert (View image)
CAS RN 22465-48-1
Reaxys Registry Number 19236547
PubChem Substance ID 253661238
Merck Index (14) 4809
MDL Number

MFCD00082532

Specifications
Appearance Orange to Brown to Dark red powder to crystal
Purity(HPLC) min. 90.0 area%
Purity(Chelometric Titration) min. 95.0 %(calcd.on dried substance)
Drying loss max. 12.0 %
Properties (reference)
Maximum Absorption Wavelength 350(AcOH buffer Sol. pH4.5) nm
Solubility (insoluble in) Ether
GHS
Pictogram Pictogram
Signal Word Warning
Hazard Statements H351 : Suspected of causing cancer.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P202 : Do not handle until all safety precautions have been read and understood.
P201 : Obtain special instructions before use.
P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection.
P308 + P313 : IF exposed or concerned: Get medical advice/ attention.
P405 : Store locked up.
Related Laws:
RTECS# GG3740000
Transport Information:
HS Number 2936.26.0000
Application
Hydroxocobalamin Acetate: Long Acting Vitamin B12 Physiological Equivalent Form

Vitamin B12 exists in four major physiological equivalent forms referred to collectively as cobalamins; hydroxocobalamin acetate, cyanocobalamin [C0449], methylcobalamin [M2742], and 5’-deoxyadenosylcobalamine. An intramuscular injection of hydroxocobalamin acetate produces higher serum levels than the same dose of cyanocobalamin, and these levels are well maintained. Cobalamins function as a coenzyme in a number of reactions, including the oxidation of fatty acids and the synthesis of DNA. They also works in conjugation with folic acid [F0043] (Vitamin B9) in the synthesis of the amino acid L-methionine [M0099] and it required for normal production of red blood cells. Although cobalamins are necessary for nervous system maintenance, the mechanisms are not entirely known. Cobalamins can be used to prevent or treat pathology arising from a lack of vitamin B12. (The product is for research purpose only.)

References


PubMed Literature


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