Coronaviruses are enveloped viruses with a positive-sense single-stranded RNA genome and a nucleocapsid of helical symmetry.¹⁾ Coronaviruses cause respiratory tract infections in humans, with most severe cases triggered by SARS, MERS, and, recently, COVID-19 (while the disease is named COVID-19, the virus that causes it was named SARS-CoV-2).²⁾ The lungs are the organs most affected by COVID-19 because the virus (using a special surface glycoprotein) accesses host cells via the enzyme ACE2, which is most abundant in the type II alveolar cells of the lungs.³⁾ Some of the trends in COVID-19 pharmaceutical development include the search for the viral proteases 3CLpro or PLpro inhibitors, viral protein expression inhibitors, viral entry to host cells inhibitors, as well as inhibitors of viral replication.⁴⁾

TCI offers many antiviral agents useful for research and experiment. Currently reported mechanisms and target virus types are summarized below. Literature information is also provided on the "Application" tab in the product details page viewable from the link of Product Number.